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. 1979 Dec 20;7(8):2177–2188. doi: 10.1093/nar/7.8.2177

Cleavage of single-stranded DNA by the A and A* proteins of bacteriophage phi X174.

S A Langeveld, A D van Mansfeld, J M de Winter, P J Weisbeek
PMCID: PMC342378  PMID: 160544

Abstract

The purified A protein and A* protein of bacteriophage phi X174 have been tested for endonuclease activity on single stranded viral phi X174 DNA. The A protein (55.000 daltons) nicks single-stranded DNA in the same way and at the same place as it does superhelical RFI DNA, at the origin of DNA replication. The A* protein (37.000 daltons) can cleave the single-stranded viral DNA at many different sites. It has however a strong preference for the origin of replication. Both proteins generate 3'OH ends and blocked 5' termini at the nick site.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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