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. 1975 Jun;2(6):905–913. doi: 10.1093/nar/2.6.905

Isolation of endonuclease from mammalian cells by DNA - cellulose chromatography.

A Caputo, G Zupi, A Clanciulli
PMCID: PMC343477  PMID: 1144065

Abstract

By means of DNA-cellulose chromatography an enzyme with endonucleolytic activity has been isolated from nuclear acidic protein fraction of mammalian cells. The main active fraction, eluted at 0.7 M NaCl, effects the velocity sedimentation of UV-irradiated and alkylated DNA, resulting in a decrease of the molecular weight. The fraction is completely inactive using native as well as heat-denatured DNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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