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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1984 Feb;81(4):1203–1207. doi: 10.1073/pnas.81.4.1203

Developmental regulation of cytokeratins in cells of the rat mammary gland studied with monoclonal antibodies.

R Allen, R Dulbecco, P Syka, M Bowman, B Armstrong
PMCID: PMC344794  PMID: 6199793

Abstract

We have isolated two monoclonal antibodies to cytokeratins and determined their cell specificities. They display interesting localization within the rat mammary gland. One (1A10) shows specificity for myoepithelial cells; the other (24B42) is specific for lumenal cells at various stages of development. These two monoclonal antibodies and three others to cytokeratin previously isolated were used in conjunction with antibodies to myosin and collagen IV to confirm and extend our previous findings on epithelial cell types and development within the mammary gland.

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Selected References

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