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. 1984 Feb;81(3):649–653. doi: 10.1073/pnas.81.3.649

Transcripts of human HLA gene fragments lacking the 5'-terminal region in transfected mouse cells.

O Yoshie, H Schmidt, P Lengyel, E S Reddy, W R Morgan, S M Weissman
PMCID: PMC344892  PMID: 6322158

Abstract

Clones of mouse L cells transfected with a human HLA-B7 gene fragment lacking the 5' segment of exon 2 and all upstream sequences express HLA-specific transcripts of various lengths. These include species that correspond in size to full-length HLA-B7 mRNA. The level of these transcripts is increased in cells treated with interferon. It is probable that the full-length transcripts arise as a result of the linkage of the HLA-B7 gene fragments with DNA segments providing transcription initiation or polyadenylylation signals.

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Selected References

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