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. 1982 Oct;79(19):6056–6059. doi: 10.1073/pnas.79.19.6056

Similarity of secretory protein I from parathyroid gland to chromogranin A from adrenal medulla.

D V Cohn, R Zangerle, R Fischer-Colbrie, L L Chu, J J Elting, J W Hamilton, H Winkler
PMCID: PMC347051  PMID: 6821132

Abstract

We have compared the amino acid and carbohydrate compositions, partial amino acid sequences, immunological crossreactivity, and physical properties of secretory protein I of the parathyroid gland and chromogranin A of adrenal gland. This comparison indicates that these proteins are similar molecules. Because secretory protein I is present in secretory granules containing parathormone and is cosecreted with the hormone, and because chromogranin A is contained within chromaffin granules and, likewise, is secreted with the catecholamines, the present observations raise the possibility that this class of protein plays a general role in hormone secretion or storage mechanisms.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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