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. 1982 Sep;37(3):891–894. doi: 10.1128/iai.37.3.891-894.1982

Different pig phenotypes affect adherence of Escherichia coli to jejunal brush borders by K88ab, K88ac, or K88ad antigen.

I G Bijlsma, A de Nijs, C van der Meer, J F Frik
PMCID: PMC347621  PMID: 6752028

Abstract

At least five different porcine phenotypes were distinguished with the three serological variants of the K88 antigen in the brush border adhesion test. Pigs of one phenotype (A) are susceptible to adherence of all three variants, pigs of three phenotypes are susceptible to only two (B and C) or one (D) of the K88 variants, and pigs of one phenotype (E) are entirely resistant to adhesion of K88 antigen did not interfere with the adhesion of K88ab- or K88ac-positive Escherichia coli, whereas in most cases K88ab and K88ac antigen completely blocked the adhesion of K88ad-positive E. coli. Likewise, K88ab antigen blocked the adhesion of K88ac-producing E. coli to both type A and type B brush borders, and vice versa.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chidlow J. W., Porter P. Intestinal defence of the neonatal pig: interrelationship of gut and mammary function providing surface immunity against colibacillosis. Vet Rec. 1979 Jun 2;104(22):496–500. doi: 10.1136/vr.104.22.496. [DOI] [PubMed] [Google Scholar]
  2. Cook B., Hunter R. H., Kelly A. S. Steroid-binding proteins in follicular fluid and peripheral plasma from pigs, cows and sheep. J Reprod Fertil. 1977 Sep;51(1):65–71. doi: 10.1530/jrf.0.0510065. [DOI] [PubMed] [Google Scholar]
  3. Evans P. A., Newby T. J., Stokes C. R., Patel D., Bourne F. J. Antibody response of the lactating sow to oral immunization with Escherichia coli. Scand J Immunol. 1980;11(4):419–429. doi: 10.1111/j.1365-3083.1980.tb00008.x. [DOI] [PubMed] [Google Scholar]
  4. Guinée P. A., Jansen W. H. Behavior of Escherichia coli K antigens K88ab, K88ac, and K88ad in immunoelectrophoresis, double diffusion, and hemagglutination. Infect Immun. 1979 Mar;23(3):700–705. doi: 10.1128/iai.23.3.700-705.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. ORSKOV I., ORSKOV F., SOJKA W. J., WITTIG W. K ANTIGENS K88AB(L) AND K88AC(L) IN E. COLI. A NEW O ANTIGEN: 0147 AND A NEW K ANTIGEN: K89(B). Acta Pathol Microbiol Scand. 1964;62:439–447. doi: 10.1111/apm.1964.62.3.439. [DOI] [PubMed] [Google Scholar]
  6. Rutter J. M., Burrows M. R., Sellwood R., Gibbons R. A. A genetic basis for resistance to enteric disease caused by E. coli. Nature. 1975 Sep 11;257(5522):135–136. doi: 10.1038/257135a0. [DOI] [PubMed] [Google Scholar]
  7. Sellwood R., Gibbons R. A., Jones G. W., Rutter J. M. Adhesion of enteropathogenic Escherichia coli to pig intestinal brush borders: the existence of two pig phenotypes. J Med Microbiol. 1975 Aug;8(3):405–411. doi: 10.1099/00222615-8-3-405. [DOI] [PubMed] [Google Scholar]
  8. Wilson M. R., Hohmann A. W. Immunity to Escherichia coli in pigs: adhesion of enteropathogenic Escherichia coli to isolated intestinal epithelial cells. Infect Immun. 1974 Oct;10(4):776–782. doi: 10.1128/iai.10.4.776-782.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]

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