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. 1980 Apr;77(4):1823–1827. doi: 10.1073/pnas.77.4.1823

Nucleotide sequence of ilvGEDA operon attenuator region of Escherichia coli.

F E Nargang, C S Subrahmanyam, H E Umbarger
PMCID: PMC348600  PMID: 6990415

Abstract

The nucleotide sequence of the DNA thought to contain the control region for the ilvGEDA operon in Escherichia coli has been determined by the Maxam-Gilbert procedure. The sequence includes a region that, upon transcription, would yield a leader transcript specifying a peptide 32 residues long. This putative peptide would contain four leucine, five isoleucine, and six valine residues. A model is proposed that correlates the multivalent control of the ilvGEDA operon with the extent to which this leader transcript is translated. In vitro transcription experiments yielded a transcript of about 183 nucelotides, compatible with the predictions of the model.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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