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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1980 Jul;77(7):4180–4184. doi: 10.1073/pnas.77.7.4180

Scale-invariance in reaction-diffusion models of spatial pattern formation.

H G Othmer, E Pate
PMCID: PMC349794  PMID: 6933464

Abstract

We propose a reaction-diffusion model of spatial pattern formation whose solutions can exhibit scale-invariance over any desired range for suitable choices of parameters in the model. The model does not invoke preset polarity or any other ad hoc distinction between cells and provides a solution to the French flag problem without sources at the boundary. Furthermore, patterns other than the polar pattern that usually arises first in a growing one-dimensional system described by Turing's model can be obtained. Evidence is given that suggests that the model may apply in the slug stage of Dictyostelium discoideum.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Browne C. L., Wiley H. S., Dumont J. N. Oocyte-follicle cell gap junctions in Xenopus laevis and the effects of gonadotropin on their permeability. Science. 1979 Jan 12;203(4376):182–183. doi: 10.1126/science.569364. [DOI] [PubMed] [Google Scholar]
  2. Caveney S. Intercellular communication in insect development is hormonally controlled. Science. 1978 Jan 13;199(4325):192–195. doi: 10.1126/science.202023. [DOI] [PubMed] [Google Scholar]
  3. Meinhardt H. Models for the ontogenetic development of higher organisms. Rev Physiol Biochem Pharmacol. 1978;80:47–104. doi: 10.1007/3540084665_2. [DOI] [PubMed] [Google Scholar]
  4. Wolpert L. Positional information and pattern formation. Curr Top Dev Biol. 1971;6(6):183–224. doi: 10.1016/s0070-2153(08)60641-9. [DOI] [PubMed] [Google Scholar]
  5. Wolpert L. Positional information and the spatial pattern of cellular differentiation. J Theor Biol. 1969 Oct;25(1):1–47. doi: 10.1016/s0022-5193(69)80016-0. [DOI] [PubMed] [Google Scholar]

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