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. 1980 Dec;77(12):7311–7314. doi: 10.1073/pnas.77.12.7311

Calmodulin activation of plant microsomal Ca2+ uptake

Peter Dieter 1, Dieter Marmé 1
PMCID: PMC350492  PMID: 16592937

Abstract

The active ATP-dependent uptake of Ca2+ into a plasma membrane-enriched microsomal fraction from plants is stimulated by the addition of plant as well as bovine brain calmodulin. This stimulation occurs only when the microsomes are prepared in the presence of EDTA. Plant calmodulin also activates the bovine brain 3′,5′-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17). Mitochondrial Ca2+ accumulation is not affected by calmodulin. The calmodulin-mediated activation of microsomal Ca2+ uptake is abolished by the antipsychotic drug fluphenazine, whereas the calmodulin-independent Ca2+ uptake is only slightly decreased.

Keywords: zucchini squash; bovine brain; 3′,5′-cyclic-nucleotide phosphodiesterase; fluphenazine

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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