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. 1982 Mar;35(3):1018–1023. doi: 10.1128/iai.35.3.1018-1023.1982

Mutant of Bordetella pertussis which lacks ability to produce filamentous hemagglutinin.

M Watanabe, Y Nakase
PMCID: PMC351149  PMID: 6279510

Abstract

Mutant cultures that lacked the ability to produce filamentous hemagglutinin were obtained by UV irradiation of Bordetella pertussis strain 18-323. Various biological activities of these mutants were compared with those of the parent culture. It was found that the leukocytosis-promoting, histamine-sensitizing, and mouse-protecting activities of the mutants were similar to those of the parent strain but that the virulence to mice was lower. The results seemed to rule out fimbrial hemagglutinin as a protective antigen when the ability to protect mice was measured by the intracerebral challenge test.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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