Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1977 Feb;11(2):271–276. doi: 10.1128/aac.11.2.271

Evaluation of the Performance Parameters of a Prediluted, Quantitative Antibiotic Susceptibility Test Device

Richard C Tilton *, Henry D Isenberg 2
PMCID: PMC351967  PMID: 848934

Abstract

A multiwelled plastic strip containing prediluted antibiotics was tested. Antibiotics available at the time of testing included ampicillin, penicillin, methicillin, erythromycin, clindamycin, tetracycline, and minocycline. The effects of inoculum size, inoculum volume, temperature, and time of incubation were determined. A limited clinical evaluation using laboratory strains of selected bacteria proved this product to be a rapid, economical, and reliable method for the determination of the minimal inhibitory concentration of antibiotics.

Full text

PDF
274

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bauer A. W., Kirby W. M., Sherris J. C., Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966 Apr;45(4):493–496. [PubMed] [Google Scholar]
  2. Ericsson H. M., Sherris J. C. Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;217(Suppl):1+–1+. [PubMed] [Google Scholar]
  3. Gavan T. L., Town M. A. A microdilution method for antibiotic susceptibility testing: an evaluation. Am J Clin Pathol. 1970 Jun;53(6):880–885. doi: 10.1093/ajcp/53.6.880. [DOI] [PubMed] [Google Scholar]
  4. MacLowry J. D., Marsh H. H. Semiautomatic microtechnique for serial dilution-antibiotic sensitivity testing in the clinical laboratory. J Lab Clin Med. 1968 Oct;72(4):685–687. [PubMed] [Google Scholar]
  5. Tilton R. C., Lieberman L., Gerlach E. H. Microdilution antibiotic susceptibility test: examination of certain variables. Appl Microbiol. 1973 Nov;26(5):658–665. doi: 10.1128/am.26.5.658-665.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES