Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1978 Sep;14(3):498–499. doi: 10.1128/aac.14.3.498

Penetration of Clindamycin into Decubitus Ulcers

Stephen A Berger 1, Michael Barza 2, Jane Haher 1, James J McFarland 1, Samuel Louie, Anne Kane 2
PMCID: PMC352490  PMID: 708028

Abstract

Forty tissue samples, primarily of skin and bone, were obtained from 29 patients undergoing excision of decubitus ulcers after intravenous injection of 600 mg of clindamycin. Antibiotic concentrations exceeded 2.5 μg/g in 80% of the samples. In 50% of the instances, tissue levels were greater than those simultaneously present in the serum.

Full text

PDF
499

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Galpin J. E., Chow A. W., Bayer A. S., Guze L. B. Sepsis associated with decubitus ulcers. Am J Med. 1976 Sep;61(3):346–350. doi: 10.1016/0002-9343(76)90371-5. [DOI] [PubMed] [Google Scholar]
  2. Louie T. J., Bartlett J. G., Tally F. P., Gorbach S. L. Aerobic and anaerobic bacteria in diabetic foot ulcers. Ann Intern Med. 1976 Oct;85(4):461–463. doi: 10.7326/0003-4819-85-4-461. [DOI] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES