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. 1979 Jun;15(6):813–819. doi: 10.1128/aac.15.6.813

Preliminary Studies of the Mode of Action of Arildone, a Novel Antiviral Agent

Michael F Kuhrt 1, Marilyn J Fancher 1, Venkatanarayana Jasty 1, Francis Pancic 1, Paul E Came 1
PMCID: PMC352764  PMID: 224808

Abstract

Arildone (also known as Win 38020), a novel aryl diketone, inhibited replication of herpes simplex virus type 2 in tissue culture by interfering with an event that occurs prior to 6 h postinfection. The inhibition could be partially reversed by washing. Although the exact mechanism of action is unknown, neither viral deoxyribonucleic acid nor viral proteins were synthesized in the presence of arildone.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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