Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1979 Nov;16(5):641–643. doi: 10.1128/aac.16.5.641

LY127935, a new beta-lactam antibiotic, versus Proteus, Klebsiella, Serratia, and Pseudomonas.

D J Flournoy, F A Perryman
PMCID: PMC352921  PMID: 526006

Abstract

One hundred eight clinical isolates of Proteus, Klebsiella, Serratia, and Pseudomonas spp. were tested in vitro against LY127935, cefamandole, cefoxitin, ticarcillin, carbenicillin, gentamicin, tobramycin, and amikacin by broth microdilution. The activities of LY127935 were greater than or equal to those of the other antimicrobial agents against Proteus vulgaris, Klebsiella pneumoniae, and Serratia marcescens. Inhibitions were greatest, however, for ticarcillin and carbenicillin versus Proteus morganii and gentamicin versus Pseudomonas aeruginosa.

Full text

PDF
643

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adams H. G., Stilwell G. A., Turck M. In vitro evaluation of cefoxitin and cefamandole. Antimicrob Agents Chemother. 1976 Jun;9(6):1019–1024. doi: 10.1128/aac.9.6.1019. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bauer A. W., Kirby W. M., Sherris J. C., Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966 Apr;45(4):493–496. [PubMed] [Google Scholar]
  3. Chow A. W., Bednorz D. Comparative in vitro activity of newer cephalosporins against anaerobic bacteria. Antimicrob Agents Chemother. 1978 Nov;14(5):668–671. doi: 10.1128/aac.14.5.668. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Flournoy D. J., Cunningham K. M., Rhoades E. R. Variation in response of Pseudomonas aeruginosa to combinations of gentamicin and carbenicillin. J Okla State Med Assoc. 1979 May;72(5):145–149. [PubMed] [Google Scholar]
  5. Jones R. N., Fuchs P. C. Comparison of in vitro antimicrobial activity of cefamandole and cefazolin with cephalothin against over 8,000 clinical bacterial isolates. Antimicrob Agents Chemother. 1976 Jun;9(6):1066–1069. doi: 10.1128/aac.9.6.1066. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Rylander M., Brorson J. E., Johnsson J., Norrby R. Comparison between agar and broth minimum inhibitory concentrations of cefamandole, Cefoxitin, and cefuroxime. Antimicrob Agents Chemother. 1979 Apr;15(4):572–579. doi: 10.1128/aac.15.4.572. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES