Skip to main content
Journal of Virology logoLink to Journal of Virology
. 1980 Oct;36(1):295–297. doi: 10.1128/jvi.36.1.295-297.1980

Simian virus 40-Chinese hamster kidney cell interaction. V. Cooperative effect of 5-iodo-2'-deoxyuridine and mitomycin C in the enhancement of virus replication in infected cells.

H G Suárez, C Lavialle, R Cassingena
PMCID: PMC353641  PMID: 6255213

Abstract

A cooperative effect of 5-iodo-2'-deoxyuridine and mitomycin C which amplified (10- to 50-fold) their stimulating effect on simian virus 40 replication was obtained in infected Chinese hamster kidney cells. The results indicate that these drugs act at different levels to modify the permissiveness of cells to simian virus 40.

Full text

PDF
297

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Biczysko W., Solter D., Pienkowski M., Koprowski H. Interactions of early mouse embryos with oncogenic viruses--simian virus 40 and polyoma. I. Ultrastructural studies. J Natl Cancer Inst. 1973 Dec;51(6):1945–1954. doi: 10.1093/jnci/51.6.1945. [DOI] [PubMed] [Google Scholar]
  2. Fogel M. Induction of virus synthesis in polyoma-transformed cells by DNA antimetabolites and by irradiation after pretreatment with 5-bromodeoxyuridine. Virology. 1972 Jul;49(1):12–22. doi: 10.1016/s0042-6822(72)80003-5. [DOI] [PubMed] [Google Scholar]
  3. Jerkofsky M., Rapp F. Stimulation of adenovirus replication in simian cells in the absence of a helper virus by pretreatment of the cells with iododeoxyuridine. J Virol. 1975 Feb;15(2):253–258. doi: 10.1128/jvi.15.2.253-258.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Lavialle C. H., Suarez H. G., Morris A. G., Cassingena R. Induction of infectious virus DNA and virus particles by mitomycin C in SV40-transformed mouse cells. J Gen Virol. 1978 Oct;41(1):201–205. doi: 10.1099/0022-1317-41-1-201. [DOI] [PubMed] [Google Scholar]
  5. Lavialle C., Morris A. G., Suaárez H. G., Estrade S., Stevenet J., Cassingena R. Simian virus 40-Chinese hamster kidney cell interaction. IV. Enhanced virus replication in infected cells upon treatment with mitomycin C. J Gen Virol. 1977 Jul;36(1):137–149. doi: 10.1099/0022-1317-36-1-137. [DOI] [PubMed] [Google Scholar]
  6. Lavialle C., Stévenet J., Morris A. G., Suarez H. G., Estrade S., Salomon J. C., Cassingena R. Simian virus 40-chinese hamster kidney cell interaction. I. Relationship of chromosome changes to transformation. Arch Virol. 1975;49(2-3):127–139. doi: 10.1007/BF01317532. [DOI] [PubMed] [Google Scholar]
  7. Morris A. G., Lavialle C., Suarez H. G., Stevenet J., Estrade S., Cassingena R. Simian virus 40-Chinese hamster kidney cell interaction. III. Characteristics of chemical induction in a clone of virogenic transformed cells. J Gen Virol. 1977 Jul;36(1):123–135. doi: 10.1099/0022-1317-36-1-123. [DOI] [PubMed] [Google Scholar]
  8. Morris A. G., Lavialle C., Suárez H. G., Cassingena R. The induction of SV40-transformed chinese hamster and mouse kidney cells by mitomycin C. Intervirology. 1975;5(5):305–312. doi: 10.1159/000149927. [DOI] [PubMed] [Google Scholar]
  9. Rakusanova T., Kaplan J. C., Smales W. P., Black P. H. Excision of viral DNA from host cell DNA after induction of simian virus 40-transformed hamster cells. J Virol. 1976 Jul;19(1):279–285. doi: 10.1128/jvi.19.1.279-285.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Staal S. P., Rowe W. P. Enhancement of adenovirus infection in WI-38 and AGMK cells by pretreatment of cells with 5-iododeoxyuridine. Virology. 1975 Apr;64(2):513–519. doi: 10.1016/0042-6822(75)90128-2. [DOI] [PubMed] [Google Scholar]
  11. Suárez H. G., Morris A. G., Lavialle C., Cassingena R. Enhanced SV 40-virus replication in chinese hamster kidney cells pretreated with 5-iodo-2'-deoxyuridine. Arch Virol. 1976;50(3):249–253. doi: 10.1007/BF01320580. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES