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. 1977 Jan;21(1):1–6. doi: 10.1128/jvi.21.1.1-6.1977

Streptomycin-resistant Escherichia coli mutant temperature sensitive for the production of Qbeta-infective particles.

H Engelberg-Kulka, L Dekel, M Israeli-Reches
PMCID: PMC353784  PMID: 319250

Abstract

A streptomycin-resistant Escherichia coli mutant has been isolated that is temperature sensitive for Qbeta phage, but not for the group I RNA phages f2, MS2, and R17. The growth of Qbeta in the mutant at the nonpermissive temperature (42 degrees C) results in the release of a near-normal burst of noninfectious particles that cosediment with Qbeta in a sucrose gradient. It is assumed that the mutant is defective at elevated temperatures in the suppression of nonsense codons, thereby producing Qbeta-like particles which are noninfectious because of the lack of the read-through protein A1.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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