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. 1978 Nov;28(2):518–523. doi: 10.1128/jvi.28.2.518-523.1978

Transcriptional mapping of rabies virus in vivo.

A Flamand, J F Delagneau
PMCID: PMC354300  PMID: 722860

Abstract

Synthesis of the proteins of rabies virus was studied in hamster cells infected with UV-irradiated virus. The UV target size of genes L, N, M1, and M2 was measured during primary transcription. Except for N, the target size of the remaining genes was considerably larger than that of their physical sizes. The data fit the hypothesis that four genes occupy a single transcriptional unit and that transcription of rabies virus proceeds in the order N, M1, M2, and L.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abraham G., Banerjee A. K. Sequential transcription of the genes of vesicular stomatitis virus. Proc Natl Acad Sci U S A. 1976 May;73(5):1504–1508. doi: 10.1073/pnas.73.5.1504. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ball L. A. Transcriptional mapping of vesicular stomatitis virus in vivo. J Virol. 1977 Jan;21(1):411–414. doi: 10.1128/jvi.21.1.411-414.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Ball L. A., White C. N. Order of transcription of genes of vesicular stomatitis virus. Proc Natl Acad Sci U S A. 1976 Feb;73(2):442–446. doi: 10.1073/pnas.73.2.442. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bonner W. M., Laskey R. A. A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. Eur J Biochem. 1974 Jul 1;46(1):83–88. doi: 10.1111/j.1432-1033.1974.tb03599.x. [DOI] [PubMed] [Google Scholar]
  5. Bramhall S., Noack N., Wu M., Loewenberg J. R. A simple colorimetric method for determination of protein. Anal Biochem. 1969 Oct 1;31(1):146–148. doi: 10.1016/0003-2697(69)90251-6. [DOI] [PubMed] [Google Scholar]
  6. Ermine A., Flamand A. Rna syntheses in BHK21 cells infected by rabies virus. Ann Microbiol (Paris) 1977 May-Jun;128A(4):477–488. [PubMed] [Google Scholar]
  7. Flamand A., Delagneau J. F., Bussereau F. An RNA polymerase activity in purified rabies virions. J Gen Virol. 1978 Jul;40(1):233–238. doi: 10.1099/0022-1317-40-1-233. [DOI] [PubMed] [Google Scholar]
  8. Flamand A., Pese D., Bussereau F. Effect of actinomycin D and cytosine arabinoside on rabies and VSV multiplication. Virology. 1977 May 1;78(1):323–327. doi: 10.1016/0042-6822(77)90103-9. [DOI] [PubMed] [Google Scholar]
  9. Kawai A. Transcriptase activity associated with rabies virion. J Virol. 1977 Dec;24(3):826–835. doi: 10.1128/jvi.24.3.826-835.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970 Aug 15;227(5259):680–685. doi: 10.1038/227680a0. [DOI] [PubMed] [Google Scholar]
  11. Madore H. P., England J. M. Rabies virus protein synthesis in infected BHK-21 cells. J Virol. 1977 Apr;22(1):102–112. doi: 10.1128/jvi.22.1.102-112.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Sokol F., Schlumberger H. D., Wiktor T. J., Koprowski H. Biochemical and biophysical studies on the nucleocapsid and on the RNA of rabies virus. Virology. 1969 Aug;38(4):651–665. doi: 10.1016/0042-6822(69)90184-6. [DOI] [PubMed] [Google Scholar]
  13. Sokol F., Stancek D., Koprowski H. Structural proteins of rabies virus. J Virol. 1971 Feb;7(2):241–249. doi: 10.1128/jvi.7.2.241-249.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]

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