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. 1975 May;15(5):1262–1266. doi: 10.1128/jvi.15.5.1262-1266.1975

Morphology of BHK-21 Cells Infected with Sindbis Virus Temperature-Sensitive Mutants in Complementation Groups D and E

Dennis T Brown 1, Jonathan F Smith 1
PMCID: PMC354582  PMID: 16789157

Abstract

BHK-21 cells infected with temperature-sensitive mutants of Sindbis virus in complementation groups D and E differed in their appearance under nonpermissive conditions. Cells infected at nonpermissive temperature with virus defective in complementation group E had nucleocapsids attached in large numbers to the inside surface of the host plasma membrane. Infection with a group D mutant produced nucleocapsids that did not attach to the plasma membrane but rather remained free in the cell cytoplasm.

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Selected References

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