Skip to main content
PMC home page
Journal of Virology logoLink to Journal of Virology
. 1975 Sep;16(3):642–651. doi: 10.1128/jvi.16.3.642-651.1975

Genetic map of the Staphylococcal bacteriophage phi11.

P J Kretschmer, J B Egan
PMCID: PMC354712  PMID: 125802

Abstract

Ten sus mutants of the staphylococcal bacteriophage phi 11, each a representative from a different complementation group, have been used in three-factor cross experiments. The results of these crosses indicate a circular genetic map for phi 11. Functional studies of the mutants have been limited to electron microscopic examinations of lysates after prophage induction (or infection). One gene is an early gene, five genes are concerned with tail formation, and three are concerned with head formation. The tenth gene is possibly a head gene. The contribution by phi 11 to the genomic content of the plasmid-phage hybrid phi 11 de has been investigated. Phi 11 de contains most of the late genes and appears to be missing a continuous phi 11 segment that includes the early gene flanked by two late genes.

Full text

PDF
650

Images in this article

648Image
on p.648

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amati P, Meselson M. Localized Negative Interference in Bacteriophage. Genetics. 1965 Mar;51(3):369–379. doi: 10.1093/genetics/51.3.369. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Botstein D., Chan R. K., Waddell C. H. Genetics of bacteriophage P22. II. Gene order and gene function. Virology. 1972 Jul;49(1):268–282. doi: 10.1016/s0042-6822(72)80028-x. [DOI] [PubMed] [Google Scholar]
  3. Brown D. T., Brown N. C., Burlingham B. T. Morphology and physical properties of Staphylococcus bacteriophage P11-M15. J Virol. 1972 Apr;9(4):664–671. doi: 10.1128/jvi.9.4.664-671.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Buchwald M., Siminovitch L. Production of serum-blocking material by mutants of the left arm of the lambda chromosome. Virology. 1969 May;38(1):1–7. doi: 10.1016/0042-6822(69)90121-4. [DOI] [PubMed] [Google Scholar]
  5. CAMPBELL A. Sensitive mutants of bacteriophage lambda. Virology. 1961 May;14:22–32. doi: 10.1016/0042-6822(61)90128-3. [DOI] [PubMed] [Google Scholar]
  6. Demerec M., Adelberg E. A., Clark A. J., Hartman P. E. A proposal for a uniform nomenclature in bacterial genetics. Genetics. 1966 Jul;54(1):61–76. doi: 10.1093/genetics/54.1.61. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Drexler H. Transduction by bacteriophage T1. Proc Natl Acad Sci U S A. 1970 Aug;66(4):1083–1088. doi: 10.1073/pnas.66.4.1083. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Edgar R. S., Lielausis I. Serological studies with mutants of phage T4D defective in genes determining tail fiber structure. Genetics. 1965 Dec;52(6):1187–1200. doi: 10.1093/genetics/52.6.1187. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. HERSHEY A. D. The production of recombinants in phage crosses. Cold Spring Harb Symp Quant Biol. 1958;23:19–46. doi: 10.1101/sqb.1958.023.01.006. [DOI] [PubMed] [Google Scholar]
  10. Ikawa S., Toyama S., Uetake H. Conditional lethal mutants of bacteriophage epsilon 34. I. Genetic map of epsilon 34. Virology. 1968 Aug;35(4):519–528. doi: 10.1016/0042-6822(68)90282-1. [DOI] [PubMed] [Google Scholar]
  11. Israel J. V., Anderson T. F., Levine M. in vitro MORPHOGENESIS OF PHAGE P22 FROM HEADS AND BASE-PLATE PARTS. Proc Natl Acad Sci U S A. 1967 Feb;57(2):284–291. doi: 10.1073/pnas.57.2.284. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Kahan E. A genetic study of temperature-sensitive mutants of the subtilis phage SP82. Virology. 1966 Dec;30(4):650–660. doi: 10.1016/0042-6822(66)90170-x. [DOI] [PubMed] [Google Scholar]
  13. Kejzlarovà J., Donini P., Eremenko-Volpe T., Graziosi F. Genetic map of bacteriophage alpha. J Virol. 1970 Jul;6(1):49–57. doi: 10.1128/jvi.6.1.49-57.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Kemp C. L., Howatson A. F., Siminovitch L. Electron microscopy studies of mutants of lambada bacteriophage. I. General description and quantitation of viral products. Virology. 1968 Nov;36(3):490–502. doi: 10.1016/0042-6822(68)90174-8. [DOI] [PubMed] [Google Scholar]
  15. King J. Assembly of the tail of bacteriophage T4. J Mol Biol. 1968 Mar 14;32(2):231–262. doi: 10.1016/0022-2836(68)90007-7. [DOI] [PubMed] [Google Scholar]
  16. Kretschmer P. J., Egan J. B. Isolation of a suppressor host bacterium in Staphylococcus aureus. J Bacteriol. 1973 Oct;116(1):84–87. doi: 10.1128/jb.116.1.84-87.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Michalke W. Erhöhte Rekombinationshäufigkeit an den Enden des T1-Chromosoms. Mol Gen Genet. 1967;99(1):12–33. doi: 10.1007/BF00306454. [DOI] [PubMed] [Google Scholar]
  18. NOVICK R. P. ANALYSIS BY TRANSDUCTION OF MUTATIONS AFFECTING PENICILLINASE FORMATION IN STAPHYLOCOCCUS AUREUS. J Gen Microbiol. 1963 Oct;33:121–136. doi: 10.1099/00221287-33-1-121. [DOI] [PubMed] [Google Scholar]
  19. NOVICK R. P., RICHMOND M. H. NATURE AND INTERACTIONS OF THE GENETIC ELEMENTS GOVERNING PENICILLINASE SYNTHESIS IN STAPHYLOCOCCUS AUREUS. J Bacteriol. 1965 Aug;90:467–480. doi: 10.1128/jb.90.2.467-480.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Novick R. P., Brodsky R. Studies on plasmid replication. I. Plasmid incompatibility and establishment in Staphylococcus aureus. J Mol Biol. 1972 Jul 21;68(2):285–302. doi: 10.1016/0022-2836(72)90214-8. [DOI] [PubMed] [Google Scholar]
  21. Novick R. Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. Virology. 1967 Sep;33(1):155–166. doi: 10.1016/0042-6822(67)90105-5. [DOI] [PubMed] [Google Scholar]
  22. Reilly B. E., Zeece V. M., Anderson D. L. Genetic study of suppressor-sensitive mutants of the Bacillus subtilis bacteriophage phi 29. J Virol. 1973 May;11(5):756–760. doi: 10.1128/jvi.11.5.756-760.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Rhoades M., MacHattie L. A., Thomas C. A., Jr The P22 bacteriophage DNA molecule. I. The mature form. J Mol Biol. 1968 Oct 14;37(1):21–40. doi: 10.1016/0022-2836(68)90071-5. [DOI] [PubMed] [Google Scholar]
  24. Sato K., Nishimune Y., Sato M., Numich R., Matsushiro A. Suppressor-sensitive mutants of coliphage phi-80. Virology. 1968 Apr;34(4):637–649. [PubMed] [Google Scholar]
  25. Sjöström J. E., Philipson L. Role of the phi 11 phage genome in competence of Staphylococcus aureus. J Bacteriol. 1974 Jul;119(1):19–32. doi: 10.1128/jb.119.1.19-32.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES