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. 1976 Aug;19(2):291–295. doi: 10.1128/jvi.19.2.291-295.1976

Induction of DNA polymerase in polyoma virus-infected mouse cells requires transcription and translation.

E Wintersberger, U Wintersberger
PMCID: PMC354864  PMID: 183005

Abstract

The induction of DNA polymerase activity and of DNA synthesis in polyoma virus-infected mouse kidney cells is inhibited by actinomycin D and cycloheximide, even in cells that are already T-antigen positive. This indicates that the induction of the DNA-synthesizing apparatus requires transcription and translation. The increase in cellular DNA polymerase activity and in the DNA synthesizing capacity follows the appearance of T-antigen only after a characteristic lag period of several hours.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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