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. 1976 Aug;19(2):668–674. doi: 10.1128/jvi.19.2.668-674.1976

Utilization of early promotors in mutant far P85 of bacteriophage T4.

W Sauerbier, K Hercules, D H Hall
PMCID: PMC354901  PMID: 957485

Abstract

We show that farP85 is a recessive mutant of T4 incapable of activating the delayed early promotors for genes 43 and 45 and that the farP85 mutation is in the same complementation group as the ts G1 mutation, which is located in the "modifier of transcription" (mot) gene.

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Selected References

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  1. Chace K. V., Hall D. H. Characterization of new regulatory mutants of bacteriophage T4. II. New class of mutants. J Virol. 1975 Apr;15(4):929–945. doi: 10.1128/jvi.15.4.929-945.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Georgopoulos C. P., Revel H. R. Studies with glucosyl transferase mutants of the T-even bacteriophages. Virology. 1971 May;44(2):271–285. doi: 10.1016/0042-6822(71)90259-5. [DOI] [PubMed] [Google Scholar]
  3. Grasso R. J., Buchanan J. M. Synthesis of early RNA in bacteriophage T4-infected Escherichia coli B. Nature. 1969 Nov 29;224(5222):882–885. doi: 10.1038/224882a0. [DOI] [PubMed] [Google Scholar]
  4. HILL R. F. A radiation-sensitive mutant of Escherichia coli. Biochim Biophys Acta. 1958 Dec;30(3):636–637. doi: 10.1016/0006-3002(58)90112-4. [DOI] [PubMed] [Google Scholar]
  5. Hercules K., Jovanovich S., Sauerbrier W. Early gene expression in bacteriophage T7. I. In vivo synthesis, inactivation, and translational utilization of early mRNA's. J Virol. 1976 Feb;17(2):642–658. doi: 10.1128/jvi.17.2.642-658.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hercules K., Sauerbier W. Transcription units in bacteriophage T4. J Virol. 1973 Oct;12(4):872–881. doi: 10.1128/jvi.12.4.872-881.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hercules K., Sauerbier W. Two modes of in vivo transcription for genes 43 and 45 of phage T4. J Virol. 1974 Aug;14(2):341–348. doi: 10.1128/jvi.14.2.341-348.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Johnson J. R., Hall D. H. Characterization of new regulatory mutants of bacteriophage T4. J Virol. 1974 Mar;13(3):666–676. doi: 10.1128/jvi.13.3.666-676.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Johnson J. R., Hall D. H. Isolation and characterization of mutants of bacteriophage T4 resistant to folate analogs. Virology. 1973 Jun;53(2):413–426. doi: 10.1016/0042-6822(73)90221-3. [DOI] [PubMed] [Google Scholar]
  10. Mattson T., Richardson J., Goodin D. Mutant of bacteriophage T4D affecting expression of many early genes. Nature. 1974 Jul 5;250(461):48–50. doi: 10.1038/250048a0. [DOI] [PubMed] [Google Scholar]
  11. Michalke H., Bremer H. RNA synthesis in Escherichia coli after irradiation with ultraviolet light. J Mol Biol. 1969 Apr 14;41(1):1–23. doi: 10.1016/0022-2836(69)90122-3. [DOI] [PubMed] [Google Scholar]
  12. O'Farrell P. Z., Gold L. M. Bacteriophage T4 gene expression. Evidence for two classes of prereplicative cistrons. J Biol Chem. 1973 Aug 10;248(15):5502–5511. [PubMed] [Google Scholar]
  13. Salser W., Bolle A., Epstein R. Transcription during bacteriophage T4 development: a demonstration that distinct subclasses of the "early" RNA appear at different times and that some are "turned off" at late times. J Mol Biol. 1970 Apr 28;49(2):271–295. doi: 10.1016/0022-2836(70)90246-9. [DOI] [PubMed] [Google Scholar]
  14. Sauerbier W., Hercules K. Control of gene function in bacteriophage T4. IV. Post-transcriptional shutoff of expression of early genes. J Virol. 1973 Sep;12(3):538–547. doi: 10.1128/jvi.12.3.538-547.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Sauerbier W., Millette R. L., Hackett P. B., Jr The effects of ultraviolet irradiation on the transcription of T4 DNA. Biochim Biophys Acta. 1970;209(2):368–386. doi: 10.1016/0005-2787(70)90735-5. [DOI] [PubMed] [Google Scholar]
  16. Schmidt D. A., Mazaitis A. J., Kasai T., Bautz E. K. Involvement of a phage T4 sigma factor and an anti-terminator protein in the transcription of early T4 genes in vivo. Nature. 1970 Mar 14;225(5237):1012–1016. doi: 10.1038/2251012a0. [DOI] [PubMed] [Google Scholar]
  17. Sippel A., Hartmann G. Mode of action of rafamycin on the RNA polymerase reaction. Biochim Biophys Acta. 1968 Mar 18;157(1):218–219. doi: 10.1016/0005-2787(68)90286-4. [DOI] [PubMed] [Google Scholar]
  18. Studier F. W. Bacteriophage T7. Science. 1972 Apr 28;176(4033):367–376. doi: 10.1126/science.176.4033.367. [DOI] [PubMed] [Google Scholar]

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