Abstract
6-(p-Hydroxyphenylazo)-uracil (HPUra), an inhibitor of semiconservative deoxyribonucleic acid (DNA) synthesis in Bacillus subtilis, does not prevent (but slightly reduces the rate of) replication of the uracil-containing DNA phage PBS2. Our observations are consistent with the hypothesis that all B. subtilis phages which are resistant to HPUra are able to induce a new DNA polymerase activity.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brown N. C. 6-(p-hydroxyphenylazo)-uracil: a selective inhibitor of host DNA replication in phage-infected Bacillus subtilis. Proc Natl Acad Sci U S A. 1970 Nov;67(3):1454–1461. doi: 10.1073/pnas.67.3.1454. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brown N. C. Inhibition of bacterial DNA replication by 6-(p-hydroxyphenylazo)-uracil: differential effect on repair and semi-conservative synthesis in Bacillus subtilis. J Mol Biol. 1971 Jul 14;59(1):1–16. doi: 10.1016/0022-2836(71)90409-8. [DOI] [PubMed] [Google Scholar]
- Brown N. C., Wisseman C. L., 3rd, Matsushita T. Inhibition of bacterial DNA replication by 6-(p-hydroxy-phenylazo)-uracil. Nat New Biol. 1972 May 17;237(72):72–74. doi: 10.1038/newbio237072a0. [DOI] [PubMed] [Google Scholar]
- Marcus M., Newlon M. C. Control of DNA synthesis in Bacillus subtilis by phage phi e. Virology. 1971 Apr;44(1):83–93. doi: 10.1016/0042-6822(71)90155-3. [DOI] [PubMed] [Google Scholar]
- Price A. R., Cook S. J. New deoxyribonucleic acid polymerase induced by Bacillus subtilis bacteriophage PBS2. J Virol. 1972 Apr;9(4):602–610. doi: 10.1128/jvi.9.4.602-610.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Price A. R., Frabotta M. Resistance of bacteriophage PBS2 infection to rifampicin, an inhibitor of Bacillus subtilis RNA synthesis. Biochem Biophys Res Commun. 1972 Sep 26;48(6):1578–1585. doi: 10.1016/0006-291x(72)90894-7. [DOI] [PubMed] [Google Scholar]
- Rutberg L., Armentrout R. W., Jonasson J. Unrelatedness of temperate Bacillus subtilis bacteriophages SP02 and phi105. J Virol. 1972 May;9(5):732–737. doi: 10.1128/jvi.9.5.732-737.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yehle C. O., Ganesan A. T. Deoxyribonucleic acid synthesis in bacteriophage SPO1-infected Bacillus subtilis. I. Bacteriophage deoxyribonucleic acid synthesis and fate of host deoxyribonucleic acid in normal and polymerase-deficient strains. J Virol. 1972 Feb;9(2):263–272. doi: 10.1128/jvi.9.2.263-272.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]