Skip to main content
Journal of Virology logoLink to Journal of Virology
. 1973 Feb;11(2):345–350. doi: 10.1128/jvi.11.2.345-350.1973

On the Question of Crown-Gall Tumor Initiation by DNA of Bacteriophage PS8

Rolf Beiderbeck 1,2,1, Gary T Heberlein 1,2,2, James A Lippincott 1,2
PMCID: PMC355103  PMID: 4688706

Abstract

DNA of Agrobacterium tumefaciens bacteriophage PS8 was isolated by using several procedures. Whole phage and phage DNA were tested for tumor-inducing ability on 10 species of plants with various additions to assist such activity. The reported tumorigenicity of phage PS8 DNA could not be confirmed, and no evidence to implicate phage PS8 involvement in tumor initiation was obtained.

Full text

PDF
346

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BEARDSLEY R. E. Lysogenicity in Agrobacterium tumefaciens. J Bacteriol. 1960 Aug;80:180–187. doi: 10.1128/jb.80.2.180-187.1960. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. GIERER A., SCHRAMM G. Infectivity of ribonucleic acid from tobacco mosaic virus. Nature. 1956 Apr 14;177(4511):702–703. doi: 10.1038/177702a0. [DOI] [PubMed] [Google Scholar]
  3. LIPPINCOTT J. A., HEBERLEIN G. T. THE INDUCTION OF LEAF TUMORS BY AGROBACTERIUM TUMEFACIENS. Am J Bot. 1965 Apr;52:396–403. [PubMed] [Google Scholar]
  4. Leff J., Beardsley R. E. Action tumorigène de l'acide nucleique d'un bactériophage présent dans les cultures de tissu tumoral de tournesol (Helianthus annus) C R Acad Sci Hebd Seances Acad Sci D. 1970 May 20;270(20):2505–2507. [PubMed] [Google Scholar]
  5. Lippincott J. A., Lippincott B. B., Chang C. C. Promotion of crown-gall tumor growth by lysopine, octopine, nopaline, and carnosine. Plant Physiol. 1972 Feb;49(2):131–137. doi: 10.1104/pp.49.2.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Lippincott J. A., Lippincott B. B. Enhanced tumor initiation by mixtures of tumorigenic and nontumorigenic strains of agrobacterium. Infect Immun. 1970 Nov;2(5):623–630. doi: 10.1128/iai.2.5.623-630.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Milani V. J., Heberlein G. T. Transfection in Agrobacterium tumefaciens. J Virol. 1972 Jul;10(1):17–22. doi: 10.1128/jvi.10.1.17-22.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Parsons C. L., Beardsley R. E. Bacteriphage activity in homogenates of crown gall tissue. J Virol. 1968 Jun;2(6):651–651. doi: 10.1128/jvi.2.6.651-.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Takebe I., Otsuki Y. Infection of tobacco mesophyll protoplasts by tobacco mosaic virus. Proc Natl Acad Sci U S A. 1969 Nov;64(3):843–848. doi: 10.1073/pnas.64.3.843. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Yamamoto K. R., Alberts B. M., Benzinger R., Lawhorne L., Treiber G. Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification. Virology. 1970 Mar;40(3):734–744. doi: 10.1016/0042-6822(70)90218-7. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES