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. 1974 Apr;13(4):809–817. doi: 10.1128/jvi.13.4.809-817.1974

Cleavage of a Viral Envelope Precursor During the Morphogenesis of Sindbis Virus

Kenneth J Jones 1, Marilynn R F Waite 1, H R Bose 1
PMCID: PMC355379  PMID: 4821491

Abstract

In cells infected with a temperature-sensitive mutant of Sindbis virus, the cleavage of the precursor to one of the viral envelope proteins does not occur at the nonpermissive temperature. This precursor is found associated with the plasma membrane fraction obtained from the infected cell. Since this is the site at which the virus matures, this finding suggests that during Sindbis virus replication the precursor to the smaller proteins associates with the cell membrane and is then cleaved during the maturation of the virus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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