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. 1974 Oct;14(4):733–739. doi: 10.1128/jvi.14.4.733-739.1974

Comparative Studies on Functions of Human Adenovirus Type 12 and Its Low Oncogenic Mutant Virions

Hisanori Ezoe 1, Stanley Mak 1
PMCID: PMC355576  PMID: 4607584

Abstract

Physical and biological properties of highly oncogenic human adenovirus type 12 were compared with a low oncogenic mutant (cyt mutant). Parental and cyt mutant virions had very similar density and DNA size. However, the parental strain virion preparations contained a much higher proportion of defective virions (capable of cell killing, but not able to induce T- or V-antigen) than cyt mutant stock. It was also found that cyt mutant had a reduced virus yield in several human cell lines compared with the parental strain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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