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. 1972 Jan;9(1):102–109. doi: 10.1128/jvi.9.1.102-109.1972

Genome of Sindbis Virus

B M Arif 1, P Faulkner 1
PMCID: PMC356268  PMID: 5061986

Abstract

32P-labeled ribonucleic acid (RNA) from purified Sindbis virus was examined for the presence of hidden breaks. Viral RNA was treated with acid at pH 2.9 or with formaldehyde and was analyzed on sucrose gradients or by polyacrylamide gel electrophoresis. The sedimentation pattern and mobility on polyacrylamide gels of the 42S RNA was unaffected by heating and quick cooling and was not altered by denaturing agents such as dimethyl sulfoxide and urea. No evidence that Sindbis RNA is a polyaggregate of fragments was obtained. It is concluded that the genome consists of a continuous length of single-stranded polynucleotide.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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