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. 1972 Dec;10(6):1231–1235. doi: 10.1128/jvi.10.6.1231-1235.1972

The Glycoprotein of Vesicular Stomatitis Virus Is the Antigen That Gives Rise to and Reacts with Neutralizing Antibody

J Michael Kelley 1, Suzanne U Emerson 1, Robert R Wagner 1
PMCID: PMC356606  PMID: 4118869

Abstract

The glycoprotein, but no other virion protein, of vesicular stomatitis virus was solubilized by the nonionic detergent Triton X-100 in low ionic strength buffer. The solubilized viral glycoprotein induced the synthesis of antibody that formed a single precipitin line with the glycoprotein and that neutralized the infectivity of the virus. The neutralizing activity of the antibody was efficiently blocked by purified glycoprotein.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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