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. 1973 Dec;12(6):1314–1324. doi: 10.1128/jvi.12.6.1314-1324.1973

Lack of Sequence Homology Among RNAs of Avian Leukosis-Sarcoma Viruses, Reticuloendotheliosis Viruses, and Chicken Endogenous RNA-Directed DNA Polymerase Activity

Chil-Yong Kang 1, Howard M Temin 1
PMCID: PMC356773  PMID: 4128378

Abstract

The relatedness of the RNAs of the three avian systems, including six avian leukosis-sarcoma viruses, four reticuloendotheliosis viruses, and the microsome fraction of normal uninfected chicken embryo cells, containing RNA and a DNA polymerase have been studied by nucleic acid hybridization. All six avian leukosis-sarcoma viruses have closely related nucleotide sequences; and all four reticuloendotheliosis viruses have closely related nucleotide sequences. But, almost no similarities were detected between the RNAs of avian leukosis-sarcoma viruses and reticuloendotheliosis viruses. The RNA template of the endogenous RNA-directed DNA polymerase activity of normal uninfected chicken cells had no detectable relationship to RNAs of avian leukosis-sarcoma and reticuloendotheliosis viruses.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Altaner C., Temin H. M. Carcinogenesis by RNA sarcoma viruses. XII. A quantitative study of infection of rat cells in vitro by avian sarcoma viruses. Virology. 1970 Jan;40(1):118–134. doi: 10.1016/0042-6822(70)90384-3. [DOI] [PubMed] [Google Scholar]
  2. Baxter-Gabbard K. L., Campbell W. F., Padgett F., Raitano-Fenton A., Levin A. S. Avian reticuloendotheliosis virus (strain T). II. Biochemical and biophysical properties. Avian Dis. 1971 Oct-Dec;15(4):850–862. [PubMed] [Google Scholar]
  3. Britten R. J., Kohne D. E. Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. Science. 1968 Aug 9;161(3841):529–540. doi: 10.1126/science.161.3841.529. [DOI] [PubMed] [Google Scholar]
  4. Coffin J. M., Temin H. M. Comparison of Rous sarcoma virus-specific deoxyribonucleic acid polymerases in virions of Rous sarcoma virus and in Rous sarcoma virus-infected chicken cells. J Virol. 1971 May;7(5):625–634. doi: 10.1128/jvi.7.5.625-634.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Coffin J. M., Temin H. M. Hybridization of Rous sarcoma virus deoxyribonucleic acid polymerase product and ribonucleic acids from chicken and rat cells infected with Rous sarcoma virus. J Virol. 1972 May;9(5):766–775. doi: 10.1128/jvi.9.5.766-775.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Cook M. K. Cultivation of a filterable agent associated with Marek's disease. J Natl Cancer Inst. 1969 Jul;43(1):203–212. [PubMed] [Google Scholar]
  7. Davis N. L., Rueckert R. R. Properties of a ribonucleoprotein particle isolated from Nonidet P-40-treated Rous sarcoma virus. J Virol. 1972 Nov;10(5):1010–1020. doi: 10.1128/jvi.10.5.1010-1020.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Duesberg P. H., Canaani E. Complementarity between Rous sarcoma virus (RSV) RNA and the in vitro-synthesized DNA of the virus-associated DNA polymerase. Virology. 1970 Nov;42(3):783–788. doi: 10.1016/0042-6822(70)90325-9. [DOI] [PubMed] [Google Scholar]
  9. Garapin A. C., Varmus H. E., Faras A. J., Levinson W. E., Bishop J. M. RNA-directed DNA synthesis by virions of Rous sarcoma virus: further characterization of the templates and the extent of their transcription. Virology. 1973 Mar;52(1):264–274. doi: 10.1016/0042-6822(73)90414-5. [DOI] [PubMed] [Google Scholar]
  10. Haapala D. K., Fischinger P. J. Molecular relatedness of mammalian RNA tumor viruses as determined by DNA hybridization. Science. 1973 Jun 1;180(4089):972–974. doi: 10.1126/science.180.4089.972. [DOI] [PubMed] [Google Scholar]
  11. Halpern M. S., Wade E., Rucker E., Baxter-Gabbard K. L., Levine A. S., Friis R. R. A study of the relationship of reticuloendotheliosis virus to the avian leukosis-sarcoma complex of viruses. Virology. 1973 Jun;53(2):287–299. doi: 10.1016/0042-6822(73)90206-7. [DOI] [PubMed] [Google Scholar]
  12. Hanafusa T., Hanafusa H. Isolation of leukosis-type virus from pheasant embryo cells: possible presence of viral genes in cells. Virology. 1973 Jan;51(1):247–251. doi: 10.1016/0042-6822(73)90388-7. [DOI] [PubMed] [Google Scholar]
  13. Hayward W. S., Hanafusa H. Detection of avian tumor virus RNA in uninfected chicken embryo cells. J Virol. 1973 Feb;11(2):157–167. doi: 10.1128/jvi.11.2.157-167.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Kang C. Y., Temin H. M. Early DNA-RNA complex from the endogenous RNA-directed DNA polymerase activity of uninfected chicken embryos. Nat New Biol. 1973 Apr 18;242(120):206–208. doi: 10.1038/newbio242206a0. [DOI] [PubMed] [Google Scholar]
  15. Kang C. Y., Temin H. M. Endogenous RNA-directed DNA polymerase activity in uninfected chicken embryos. Proc Natl Acad Sci U S A. 1972 Jun;69(6):1550–1554. doi: 10.1073/pnas.69.6.1550. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Leong J. A., Garapin A. C., Jackson N., Fanshier L., Levinson W., Bishop J. M. Virus-specific ribonucleic acid in cells producing rous sarcoma virus: detection and characterization. J Virol. 1972 Jun;9(6):891–902. doi: 10.1128/jvi.9.6.891-902.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Ludford C. G., Purchase H. G., Cox H. W. Duck infectious anemia virus associated with Plasmodium lophurae. Exp Parasitol. 1972 Feb;31(1):29–38. doi: 10.1016/0014-4894(72)90044-6. [DOI] [PubMed] [Google Scholar]
  18. Maldonado R. L., Bose H. R. Relationship of reticuloendotheliosis virus to the avian tumor viruses: nucleic acid and polypeptide composition. J Virol. 1973 May;11(5):741–747. doi: 10.1128/jvi.11.5.741-747.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Maldonado R. L., Bose H. R. Separation of reticuloendotheliosis virus from avian tumor viruses. J Virol. 1971 Nov;8(5):813–815. doi: 10.1128/jvi.8.5.813-815.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Mizutani S., Temin H. M. Lack of serological relationship among DNA polymerases of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken cells. J Virol. 1973 Sep;12(3):440–448. doi: 10.1128/jvi.12.3.440-448.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Parsons J. T., Coffin J. M., Haroz R. K., Bromley P. A., Weissmann C. Quantitative determination and location of newly synthesized virus-specific ribonucleic acid in chicken cells infected with Rous sarcoma virus. J Virol. 1973 May;11(5):761–774. doi: 10.1128/jvi.11.5.761-774.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Peterson D. A., Baxter-Gabbard K. L., Levine A. S. Avian reticuloendotheliosis virus (strain T): V. DNA polymerase. Virology. 1972 Jan;47(1):251–254. doi: 10.1016/0042-6822(72)90259-0. [DOI] [PubMed] [Google Scholar]
  23. Sutton W. D. A crude nuclease preparation suitable for use in DNA reassociation experiments. Biochim Biophys Acta. 1971 Jul 29;240(4):522–531. doi: 10.1016/0005-2787(71)90709-x. [DOI] [PubMed] [Google Scholar]
  24. TRAGER W. A new virus of ducks interfering with development of malaria parasite (Plasmodium lophurae). Proc Soc Exp Biol Med. 1959 Jul;101(3):578–582. doi: 10.3181/00379727-101-25023. [DOI] [PubMed] [Google Scholar]
  25. Temin H. M., Baltimore D. RNA-directed DNA synthesis and RNA tumor viruses. Adv Virus Res. 1972;17:129–186. doi: 10.1016/s0065-3527(08)60749-6. [DOI] [PubMed] [Google Scholar]
  26. Temin H. M., Mizutani S. RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature. 1970 Jun 27;226(5252):1211–1213. doi: 10.1038/2261211a0. [DOI] [PubMed] [Google Scholar]
  27. Vogt P. K., Friis R. R. An avian leukosis virus related to RSV(O): properties and evidence for helper activity. Virology. 1971 Jan;43(1):223–234. doi: 10.1016/0042-6822(71)90240-6. [DOI] [PubMed] [Google Scholar]
  28. Weiss R. A., Friis R. R., Katz E., Vogt P. K. Induction of avian tumor viruses in normal cells by physical and chemical carcinogens. Virology. 1971 Dec;46(3):920–938. doi: 10.1016/0042-6822(71)90091-2. [DOI] [PubMed] [Google Scholar]
  29. Zeigel R. F., Theilen G. H., Twiehaus M. J. Electron microscopic observations on RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens, and Japanese quail. J Natl Cancer Inst. 1966 Dec;37(6):709–729. [PubMed] [Google Scholar]

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