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. 1990 Jan;10(1):382–386. doi: 10.1128/mcb.10.1.382

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes.

G Radcliffe 1, Y C Lin 1, M Julius 1, K B Marcu 1, J Stavnezer 1
PMCID: PMC360760  PMID: 2152964

Abstract

We describe the structure of the major germ line RNA transcribed from unrearranged immunoglobulin alpha heavy-chain genes in immunoglobulin M-expressing cells of the I.29 mu B-cell lymphoma, a cell line capable of switching to immunoglobulin A expression upon lipopolysaccharide treatment. This germ line alpha RNA has a small open reading frame that does not include the C alpha domain, and this RNA appears to be present on polysomes in I.29 mu cells.

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Selected References

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