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. 1990 Jan;10(1):401–404. doi: 10.1128/mcb.10.1.401

Effects of methotrexate on transfected DNA stability in mammalian cells.

M G Pallavicini 1, P S DeTeresa 1, C Rosette 1, J W Gray 1, F M Wurm 1
PMCID: PMC360766  PMID: 2403643

Abstract

The chromosomal locations, amounts, and level of expression of transfected, amplified c-myc and dihydrofolate reductase sequences were measured in cells cultured in the presence and absence of methotrexate. These studies show that the location and amount of transfected sequences, as well as the level of expression, were more variable when the cells were cultured in methotrexate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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