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. 1989 Jun;9(6):2752–2755. doi: 10.1128/mcb.9.6.2752

Regulation of tissue factor gene expression in the monocyte procoagulant response to endotoxin.

S A Gregory 1, J H Morrissey 1, T S Edgington 1
PMCID: PMC362351  PMID: 2503712

Abstract

Tissue factor is the cellular receptor and cofactor for plasma factor VIIa which initiates the coagulation protease cascade on cell surfaces. Although normally absent from all intravascular cell types, tissue factor can be induced to appear on circulating monocytes and vascular endothelial cells by specific inflammatory or immunological mediators. In this study, we have examined the regulation of endotoxin-induced tissue factor gene expression in peripheral blood monocytes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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