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. 1989 Feb;9(2):851–853. doi: 10.1128/mcb.9.2.851

Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells.

A J Fornace Jr 1, B Zmudzka 1, M C Hollander 1, S H Wilson 1
PMCID: PMC362667  PMID: 2710127

Abstract

Only a few of the genes involved in DNA repair in mammalian cells have been isolated, and induction of a DNA repair gene in response to DNA damage has not yet been established. DNA polymerase beta (beta-polymerase) appears to have a synthetic role in DNA repair after certain types of DNA damage. Here we show that the level of beta-polymerase mRNA is increased in CHO cells after treatment with several DNA-damaging agents.

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Selected References

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