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. 1988 Apr;8(4):1849–1852. doi: 10.1128/mcb.8.4.1849

Structure and expression of germ line immunoglobulin gamma 2b transcripts.

S Lutzker 1, F W Alt 1
PMCID: PMC363353  PMID: 3132612

Abstract

We have isolated a cDNA copy of a truncated C gamma 2b transcript produced by Abelson murine leukemia virus transformants that spontaneously switch from mu to gamma 2b. The initiation site of this transcript was 2 kilobases 5' to the gamma 2b switch recombination region, demonstrating its germ line origin. Nucleotide sequence analyses suggest that this transcript does not encode a protein. Expression of germ line gamma 2b transcripts in Abelson murine leukemia virus transformants and in normal spleen cells correlated with endogenous gamma 2b class switch activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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