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. 1988 May;8(5):2233–2236. doi: 10.1128/mcb.8.5.2233

Concomitant K- and N-ras gene point mutations in clonal murine lymphoma.

L E Diamond 1, I Guerrero 1, A Pellicer 1
PMCID: PMC363408  PMID: 3290653

Abstract

We have surveyed a panel of induced murine lymphomas for c-ras gene mutations. The K-ras gene seems to be preferentially activated in our system, and there are at least two examples of concomitant K- and N-ras gene mutations in the same tumor. This indicates that in some cases additional ras mutations may contribute to tumorigenesis and is evidence for a role of ras activation in tumor progression.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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