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. 1973 Oct;52(4):373–379. doi: 10.1104/pp.52.4.373

Activation and Inhibition of Ribulose 1,5-Diphosphate Carboxylase by 6-Phosphogluconate 1

Douglas K Chu a, J A Bassham a
PMCID: PMC366505  PMID: 16658565

Abstract

Ribulose 1,5-diphosphate carboxylase, when activated by preincubation with 1 mm bicarbonate and 10 mm MgCl2 in the absence of ribulose 1,5-diphosphate, remains activated for 20 minutes or longer after reaction is initiated by addition of ribulose diphosphate. If as little as 50 μm 6-phosphogluconate is added during this preincubation period, 5 minutes before the start of the reaction, a further 188% activation is observed. However, addition of 6-phosphogluconate at the same time or later than addition of ribulose diphosphate, or at any time with 50 mm bicarbonate, gives inhibition of the enzyme activity. Possible relevance of these effects in vivo regulatory effects is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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