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. 1985 Apr;5(4):885–889. doi: 10.1128/mcb.5.4.885

Characterization and developmental expression of a Drosophila ras oncogene.

B Mozer, R Marlor, S Parkhurst, V Corces
PMCID: PMC366794  PMID: 3921827

Abstract

We cloned a Drosophila melanogaster ras gene (Dmras64B) on the basis of its homology to the ras oncogen from Harvey murine sarcoma virus. This gene mapped at chromosomal position 64B on the left arm of the third chromosome. Sequencing of Dmras64B revealed extensive amino acid homology with the proteins encoded by the human and Saccharomyces cerevisiae ras genes. The coding region of the Drosophila gene is interrupted by two introns located in different positions with respect to its human counterpart. Dmras64B encodes three different RNAs (1.6, 2.1, and 2.6 kilobases long) that are constantly expressed throughout the development of the fly.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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