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. 1981 Jun;1(6):560–567. doi: 10.1128/mcb.1.6.560

Enhanced internalization of ricin in nigericin-pretreated Chinese hamster ovary cells.

B Ray 1, H C Wu 1
PMCID: PMC369699  PMID: 6965109

Abstract

Biochemical and electron microscopic autoradiographic studies with [125I] ricin have revealed that nigericin-pretreated Chinese hamster ovary cells are more efficient than untreated cells in the internalization of the toxin into the cells. These results suggest that the enhanced rate of internalization of ricin in nigericin-pretreated cells may account for the enhancement of cytotoxicity of ricin in Chinese hamster ovary cells by nigericin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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