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. 1969 Jan;3(1):17–24. doi: 10.1128/jvi.3.1.17-24.1969

Immunochemical Characterization of Plaque Mutants of Simian Virus 40

H L Ozer 1, K K Takemoto 1, R L Kirschstein 1,1, D Axelrod 1
PMCID: PMC375724  PMID: 4306300

Abstract

Analysis of large and small plaque mutants of simian virus 40 using antisera prepared against each has revealed quantitative and possibly qualitative antigenic differences for each plaque type. A sensitive micro radioisotope precipitation test permitted evaluation of immunochemical similarities and differences of capsid antigens by inhibition of precipitation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benjamini E., Shimizu M., Young J. D., Leung C. Y. Immunochemical studies on the tobacco mosaic virus protein. VI. Characterization of antibody populations following immunization with tobacco mosaic virus protein. Biochemistry. 1968 Apr;7(4):1253–1260. doi: 10.1021/bi00844a001. [DOI] [PubMed] [Google Scholar]
  2. GERLOFF R. K., HOYER B. H., McLAREN L. C. Precipitation of radiolabeled poliovirus with specific antibody and antiglobulin. J Immunol. 1962 Oct;89:559–570. [PubMed] [Google Scholar]
  3. HERZENBERG L. A., WARNER N. L., HERZENBERG L. A. IMMUNOGLOBULIN ISOANTIGENS (ALLOTYPES) IN THE MOUSE. I. GENETICS AND CROSS-REACTIONS OF THE 7S GAMMA-2A-ISOANTIGENS CONTROLLED BY ALLELES AT THE IG-1 LOCUS. J Exp Med. 1965 Mar 1;121:415–438. doi: 10.1084/jem.121.3.415. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Hare J. D., Chan J. C. Antigenic variation among polyoma viruses from different sources demonstrated by plaque neutralization. Virology. 1966 Sep;30(1):62–73. doi: 10.1016/s0042-6822(66)81010-3. [DOI] [PubMed] [Google Scholar]
  5. Koch M. A., Eggers H. J., Anderer F. A., Schlumberger H. D., Frank H. Structure of simian virus 40. I. Purification and physical characterization of the virus particle. Virology. 1967 Jul;32(3):503–510. doi: 10.1016/0042-6822(67)90302-9. [DOI] [PubMed] [Google Scholar]
  6. Mattern C. F., Takemoto K. K., DeLeva A. M. Electron microscopic observations on multiple polyoma virus-related particles. Virology. 1967 Jul;32(3):378–392. doi: 10.1016/0042-6822(67)90288-7. [DOI] [PubMed] [Google Scholar]
  7. RAPPAPORT I., SIEGEL A., HASELKORN R. INFLUENCE OF THE STATE OF SUBUNIT AGGREGATION ON THE ANTIGENIC SPECIFICITY OF TMV AND TYMV. Virology. 1965 Feb;25:325–328. doi: 10.1016/0042-6822(65)90211-4. [DOI] [PubMed] [Google Scholar]
  8. SEVER J. L. Application of a microtechnique to viral serological investigations. J Immunol. 1962 Mar;88:320–329. [PubMed] [Google Scholar]
  9. Takemoto K. K., Habel K. Hamster ascitic fluids containing complement-fixing antibody against virus-induced tumor antigens. Proc Soc Exp Biol Med. 1965 Oct;120(1):124–127. doi: 10.3181/00379727-120-30464. [DOI] [PubMed] [Google Scholar]
  10. Takemoto K. K., Kirschstein R. L., Habel K. Mutants of simian virus 40 differing in plaque size, oncogenicity, and heat sensitivity. J Bacteriol. 1966 Oct;92(4):990–994. doi: 10.1128/jb.92.4.990-994.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Takemoto K. K., Todaro G. J., Habel K. Recovery of SV40 virus with genetic markers of original inducing virus from SV40-transformed mouse cells. Virology. 1968 May;35(1):1–8. doi: 10.1016/0042-6822(68)90299-7. [DOI] [PubMed] [Google Scholar]
  12. WINOCOUR E. Purification of polyoma virus. Virology. 1963 Feb;19:158–168. doi: 10.1016/0042-6822(63)90005-9. [DOI] [PubMed] [Google Scholar]

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