Abstract
The Gilchrist and M-33 strains of rubella virus exposed in the frozen state to 137Ce or 60Co were inactivated exponentially according to “one hit” kinetics. There was no difference in the radiosensitivity of the two strains. Experimental D37 values for both strains ranged from 1.9 × 105 to 2.9 × 105 rads, and computed radiosensitive molecular weights ranged from 2.6 × 106 to 4.0 × 106 daltons.
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Selected References
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- Basilico C., Di Mayorca G. Radiation target size of the lytic and the transforming ability of polyoma virus. Proc Natl Acad Sci U S A. 1965 Jul;54(1):125–127. doi: 10.1073/pnas.54.1.125. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CUSUMANO C. L., SCHIFF G. M., SEVER J. L., HUEBNER R. J. RUBELLA VIRUS: NUCLEIC ACID STUDIES USING 5 IODO 2'-DEOXYURIDINE. J Pediatr. 1964 Jul;65:138–140. [PubMed] [Google Scholar]
- Decker C., Guir J., Kirn A. Infectivity and capacity for DNA replication of vaccinia virus irradiated by gamma-rays. J Gen Virol. 1969 Mar;4(2):221–227. doi: 10.1099/0022-1317-4-2-221. [DOI] [PubMed] [Google Scholar]
- GINOZA W., NORMAN A. Radiosensitive molecular weight of tobacco mosaic virus nucleic acid. Nature. 1957 Mar 9;179(4558):520–521. doi: 10.1038/179520a0. [DOI] [PubMed] [Google Scholar]
- JORDAN R. T., KEMPE L. L. Inactivation of some animal viruses with gamma radiation from cobalt-60. Proc Soc Exp Biol Med. 1956 Feb;91(2):212–215. doi: 10.3181/00379727-91-22215. [DOI] [PubMed] [Google Scholar]
- Jaques R. P. The inactivation of the nuclear polyhedrosis virus of Trichoplusia ni by gamma and ultraviolet radiation. Can J Microbiol. 1968 Oct;14(10):1161–1163. doi: 10.1139/m68-194. [DOI] [PubMed] [Google Scholar]
- Latarjet R., Cramer R., Montagnier L. Inactivation, by UV-, x-, and gamma-radiations, of the infecting and transforming capacities of polyoma virus. Virology. 1967 Sep;33(1):104–111. doi: 10.1016/0042-6822(67)90098-0. [DOI] [PubMed] [Google Scholar]
- MAASSAB H. F., COCHRAN K. W. INFLUENCE OF 5-FLUORODEOXYURIDINE ON GROWTH CHARACTERISTICS OF RUBELLA VIRUS. Proc Soc Exp Biol Med. 1964 Nov;117:410–413. doi: 10.3181/00379727-117-29595. [DOI] [PubMed] [Google Scholar]
- Oxford J. S., Potter C. E., Sutton R. N. Determination of the type of nucleic acid in rubella virus using 5-bromo-2'-deoxyuridine. Nature. 1965 Jul 17;207(994):324–326. doi: 10.1038/207324a0. [DOI] [PubMed] [Google Scholar]
- PARKMAN P. D., BUESCHER E. L., ARTENSTEIN M. S., MCCOWN J. M., MUNDON F. K., DRUZD A. D. STUDIES OF RUBELLA. I. PROPERTIES OF THE VIRUS. J Immunol. 1964 Oct;93:595–607. [PubMed] [Google Scholar]
- POLLEY J. R. Factors influencing inactivation of infectivity and hemagglutinin of influenza virus by gamma radiation. Can J Microbiol. 1961 Aug;7:535–541. doi: 10.1139/m61-063. [DOI] [PubMed] [Google Scholar]
- Polatnick J., Bachrach H. L. Ionizing irradiation of foot-and-mouth disease virus and its ribonucleic acid. Arch Gesamte Virusforsch. 1968;23(1):96–104. doi: 10.1007/BF01242118. [DOI] [PubMed] [Google Scholar]
- Reitman M., Tribble H. R. Inactivation of Venezuelan Equine Encephalomyelitis Virus by gamma-Radiation. Appl Microbiol. 1967 Nov;15(6):1456–1459. doi: 10.1128/am.15.6.1456-1459.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Vaheri A., Sedwick W. D., Plotkin S. A. Growth of rubella virus in BHK21 cells. II. Enhancing effect of DEAE-dextran, semicarbazide and low doses of metabolic inhibitors. Proc Soc Exp Biol Med. 1967 Aug-Sep;125(4):1092–1098. doi: 10.3181/00379727-125-32284. [DOI] [PubMed] [Google Scholar]