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. 1970 Aug;6(2):218–225. doi: 10.1128/jvi.6.2.218-225.1970

λ Mutants Which Persist as Plasmids

M Lieb 1
PMCID: PMC376111  PMID: 4925775

Abstract

Lambda phages mutated in gene N do not kill sensitive host bacteria, but persist as plasmids. Plasmids are formed by genomes containing cI+, and also by sus, ts, or c mutants of cI. Bacteria infected with two or more phage particles give rise to clones in which most of the bacteria are carriers. The introduced λ genomes replicate more than once per bacterial division until there are 10 to 20 λ plasmids per host genome. In bacteria containing both F and λ plasmids, both replicate independently, and elimination by growth in acridine orange is also independent. Carriers of λ Nsus plasmids are not immune, and there is complementation between the plasmids and superinfecting λ mutants.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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