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. 1979 Apr;76(4):1756–1759. doi: 10.1073/pnas.76.4.1756

Purification to homogeneity of camel pituitary pro-opiocortin, the common precursor of opioid peptides and corticotropin.

S Kimura, R V Lewis, L D Gerber, L Brink, M Rubinstein, S Stein, S Udenfriend
PMCID: PMC383469  PMID: 221906

Abstract

Pro-opiocortin was purified from camel pituitaries by procedures including high-performance liquid chromatography. The precursor relationship of the pure protein to the opioid peptides and to corticotropin was confirmed. Partial chemical analysis consisting of amino acid analysis and tryptic peptide mapping was carried out with the aid of sensitive fluorescence detection.

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Selected References

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