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. 1986 Nov;83(22):8713–8717. doi: 10.1073/pnas.83.22.8713

A repetitive antigen of Plasmodium falciparum that is homologous to heat shock protein 70 of Drosophila melanogaster.

A E Bianco, J M Favaloro, T R Burkot, J G Culvenor, P E Crewther, G V Brown, R F Anders, R L Coppel, D J Kemp
PMCID: PMC387001  PMID: 3095842

Abstract

We describe an antigen of Plasmodium falciparum, defined by a cDNA clone designated Ag63. The antigen is an abundant, soluble cytoplasmic polypeptide of Mr 75,000 present in all stages of asexual development in the blood and in gametocytes, but not in sporozoites. The sequence of the cDNA clone revealed that, like many other antigens of P. falciparum, it contains tandemly repeated amino acid sequences, in this case Gly-Gly-Met-Pro. However, the rest of the sequence is 70% homologous at the amino acid level to the heat shock protein hsp70 of Drosophila melanogaster.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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