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. 1974 Jan;71(1):225–229. doi: 10.1073/pnas.71.1.225

Activation of Transcription of hut DNA by Glutamine Synthetase

Bonnie Tyler 1, Albert B Deleo 1, Boris Magasanik 1
PMCID: PMC387970  PMID: 4149344

Abstract

The correct transcription of the hut (histidine utilization) operon DNA of Salmonella typhimurium requires activation either by 3′:5′-cyclic adenosine monophosphate and catabolite-activating protein or by nonadenylylated glutamine synthetase (EC 6.3.1.2.). Thus, glutamine synthetase plays a regulatory role distinct from its enzymatic function.

Keywords: histidine utilization (hut) operons, Salmonella typhimurium, control of glutamate-forming enzymes, cyclic AMP

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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