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. 1974 Jun;71(6):2273–2275. doi: 10.1073/pnas.71.6.2273

In Vitro Repair of Apurinic Sites in DNA

W G Verly 1, F Gossard 1, P Crine 1
PMCID: PMC388434  PMID: 4601584

Abstract

Apurinic sites disappear from DNA during an incubation of the DNA with the Escherichia coli endonuclease specific for apurinic sites, DNA polymerase I (EC 2.7.7.7.), and T4 ligase (EC 6.5.1.1). Omission of any one of these three enzymes and, in particular, omission of the endonuclease specific for apurinic sites prevents this in vitro repair.

Keywords: DNA depurination, endonuclease specific for apurinic sites, DNA repair

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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