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. 1974 Jun;71(6):2449–2452. doi: 10.1073/pnas.71.6.2449

Effects of an Antibody to a Highly Purified Na+, K+-ATPase from Canine Renal Medulla: Separation of the “Holoenzyme Antibody” into Catalytic and Cardiac Glycoside Receptor-Specific Components

John L McCans 1,2,3, Lois K Lane 1,2,3, George E Lindenmayer 1,2,3, Vincent P Butler Jr 1,2,3, Arnold Schwartz 1,2,3
PMCID: PMC388475  PMID: 4276366

Abstract

An antiserum was prepared against a highly purified Na+, K+-adenosine triphosphatase (ATP phosphohydrolase, EC 3.6.1.3). Purification and fractionation yielded two globulin components, one of which appears specific for a digitalis glycoside receptor site or binding conformation and the other for a catalytic site or conformation.

Keywords: antibody fractionation, globulin components, digitalis receptor antibody, conformation-specific antibodies

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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