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. 1971 May;68(5):977–979. doi: 10.1073/pnas.68.5.977

Initiation of DNA Synthesis in Cell Cultures by Colcemid

J M Vasiliev 1,2, I M Gelfand 1,2, V I Guelstein 1,2
PMCID: PMC389094  PMID: 5280531

Abstract

Mitotic inhibitors (colcemid, colchicine, and vinblastine) initiate DNA synthesis in dense stationary cultures of mouse embryo fibroblast-like cells. This initiation is not due to any changes in local cell population density. Relationships between the activation of proliferation and other changes of interphase fibroblast-like cells produced by the mitotic inhibitors (disappearance of cytoplasmic microtubules and activation of movements of cell surface) are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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