Abstract
In the presence of over-threshold concentrations of simple neutral polymers and salts, DNA undergoes a cooperative change in its solution structure. Sedimentation studies at low DNA concentrations show that phage DNA molecules collapse into particles approaching the compactness of the contents of phage heads. The interaction between DNA and polymers is thought to be nonspecifically replusive.
Keywords: poly(vinyl pyrrolidinone), poly(ethylene oxide), T4 phage, centrifugation
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Selected References
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