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. 1971 Sep;68(9):1999–2001. doi: 10.1073/pnas.68.9.1999

The 3′-Terminal Nucleosides of the High Molecular Weight RNA of C-Type Viruses

H B Maruyama 1,*, M Hatanaka 1,†, R V Gilden 1
PMCID: PMC389334  PMID: 4332242

Abstract

Tumor virus RNAs from several mammalian and one reptilian species were purified; their 3′-terminal nucleoside was identified by separation of the trialcohols produced by periodate oxidation followed by reduction and tritiation with NaB3H4. Each virus contained uridine as the predominant terminal nucleoside. Molecular weight estimations based on the tritiation reactions were consistent with a structure consisting of four subunits.

Keywords: [3H]sodium borohydride, hamster, viper, mouse, cat

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2001

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baltimore D. RNA-dependent DNA polymerase in virions of RNA tumour viruses. Nature. 1970 Jun 27;226(5252):1209–1211. doi: 10.1038/2261209a0. [DOI] [PubMed] [Google Scholar]
  2. Duesberg P. H. Physical properties of Rous Sarcoma Virus RNA. Proc Natl Acad Sci U S A. 1968 Aug;60(4):1511–1518. doi: 10.1073/pnas.60.4.1511. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Granboulan N., Huppert J., Lacour F. Examen au microscope electronique du RNA du virus de la myeloblastose aviaire. J Mol Biol. 1966 Apr;16(2):571–575. doi: 10.1016/s0022-2836(66)80196-1. [DOI] [PubMed] [Google Scholar]
  4. Hatanaka M., Huebner R. J., Gilden R. V. DNA polymerase activity associated with RNA tumor viruses. Proc Natl Acad Sci U S A. 1970 Sep;67(1):143–147. doi: 10.1073/pnas.67.1.143. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Huebner R. J., Todaro G. J. Oncogenes of RNA tumor viruses as determinants of cancer. Proc Natl Acad Sci U S A. 1969 Nov;64(3):1087–1094. doi: 10.1073/pnas.64.3.1087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Jacobson M., Hedgcoth C. Determination of 5,6-dihydrouridine in ribonucleic acid. Anal Biochem. 1970 Apr;34(2):459–469. doi: 10.1016/0003-2697(70)90130-2. [DOI] [PubMed] [Google Scholar]
  7. Montagnier L., Goldé A., Vigier P. A possible subunit structure of Rous sarcoma virus RNA. J Gen Virol. 1969 Apr;4(3):449–452. doi: 10.1099/0022-1317-4-3-449. [DOI] [PubMed] [Google Scholar]
  8. Nishihara T., Haruna I., Watanabe I., Nozu Y., Okada Y. Comparison of coat proteins from three groups of RNA phages. Virology. 1969 Jan;37(1):153–155. doi: 10.1016/0042-6822(69)90320-1. [DOI] [PubMed] [Google Scholar]
  9. Overby L. R., Barlow G. H., Doi R. H., Jacob M., Spiegelman S. Comparison of two serologically distinct ribonucleic acid bacteriophages. II. Properties of the nucleic acids and coat proteins. J Bacteriol. 1966 Sep;92(3):739–745. doi: 10.1128/jb.92.3.739-745.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Rensing U., August J. T. The 3'-terminus and the replication of phage RNA. Nature. 1969 Nov 29;224(5222):853–856. doi: 10.1038/224853a0. [DOI] [PubMed] [Google Scholar]
  11. Robinson W. S., Robinson H. L., Duesberg P. H. Tumor virus RNA's. Proc Natl Acad Sci U S A. 1967 Sep;58(3):825–834. doi: 10.1073/pnas.58.3.825. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Temin H. M., Mizutani S. RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature. 1970 Jun 27;226(5252):1211–1213. doi: 10.1038/2261211a0. [DOI] [PubMed] [Google Scholar]

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