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. 1971 Sep;68(9):2252–2257. doi: 10.1073/pnas.68.9.2252

A Novel Closed-Circular Mitochondrial DNA with Properties of a Replicating Intermediate

Harumi Kasamatsu 1,2, Donald L Robberson 1,2, Jerome Vinograd 1,2
PMCID: PMC389395  PMID: 5289384

Abstract

A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.

Keywords: density-gradient centrifugation, electron microscopy, separated strands, ethidium bromide, mouse DNA

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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