Abstract
A systematic search has resulted in the synthesis of a class of cytokinin antimetabolites. The development and biological properties of the anticytokinins are discussed in terms of one member of the class, 3- methyl - 7 - (3 - methylbutylamino)pyrazolo[4,3 - d]- pyrimidine.
Keywords: tobacco callus, adenine analogues
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- Burrows W. J., Armstrong D. J., Kaminek M., Skoog F., Bock R. M., Hecht S. M., Dammann L. G., Leonard N. J., Occolowitz J. Isolation and identification of four cytokinins from wheat germ transfer ribonucleic acid. Biochemistry. 1970 Apr 28;9(9):1867–1872. doi: 10.1021/bi00811a001. [DOI] [PubMed] [Google Scholar]
- Gallo R. C., Whang-Peng J., Perry S. Isopentenyladenosine stimulates and inhibits mitosis of human lymphocytes treated with phytohemagglutinin. Science. 1969 Jul 25;165(3891):400–402. doi: 10.1126/science.165.3891.400. [DOI] [PubMed] [Google Scholar]
- Helgeson J. P. The cytokinins. Synthetic and naturally occurring N6-substituted adenine derivatives profoundly affect plant growth. Science. 1968 Sep 6;161(3845):974–981. doi: 10.1126/science.161.3845.974. [DOI] [PubMed] [Google Scholar]
- Hitchings G. H. Effects of allopurinol in relation to purine biosynthesis. Ann Rheum Dis. 1966 Nov;25(6 Suppl):601–607. doi: 10.1136/ard.25.suppl_6.601. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ikehara M., Murao K., Harada F., Nishimura S. Synthesis of formycin triphosphate and its incorpoartion into ribopolynucleotide by DNA-dependent RNA polymers. Biochim Biophys Acta. 1968 Jan 29;155(1):82–90. doi: 10.1016/0005-2787(68)90337-7. [DOI] [PubMed] [Google Scholar]
- Klämbt D., Thies G., Skoog F. Isolation of cytokinins from Corynebacterium fascians. Proc Natl Acad Sci U S A. 1966 Jul;56(1):52–59. doi: 10.1073/pnas.56.1.52. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Miller C. O. Evidence for the natural occurrence of zeatin and derivatives: compounds from maize which promote cell division. Proc Natl Acad Sci U S A. 1965 Oct;54(4):1052–1058. doi: 10.1073/pnas.54.4.1052. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zachau H. G. Transfer ribonucleic acids. Angew Chem Int Ed Engl. 1969 Oct;8(10):711–727. doi: 10.1002/anie.196907111. [DOI] [PubMed] [Google Scholar]